Effect of intranasal corticosteroid on pre-onset activation of eosinophils and mast cells in experimental Japanese cedar pollinosis
نویسندگان
چکیده
منابع مشابه
Effect of intranasal corticosteroid on pre-onset activation of eosinophils and mast cells in experimental Japanese cedar pollinosis.
BACKGROUND Minimal persistent inflammation (MPI) contributes to hyperreactivity in allergic rhinitis. However, little is known regarding whether pre-onset activation of eosinophils and mast cells is present or not in Japanese cedar pollinosis (JCP). Furthermore, a prophylactic effect of intranasal corticosteroids on such MPI in JCP has not been investigated. METHODS We designed a double-blind...
متن کاملMinimal persistent inflammation in Japanese cedar pollinosis and a prophylactic effect of intranasal corticosteroids
Background Low doses of allergen exposure can cause an activation of inflammatory cells in nasal mucosa without an onset of nasal symptoms, called MPI (minimal persistent inflammation). MPI contributes to hyperreactivity and subsequently onset of the full-scale symptom. However, little is known whether MPI is present in JCP (Japanese cedar pollinosis). In addition, a prophylactic effect of intr...
متن کاملAsthma in Patients With Japanese Cedar Pollinosis
Japanese cedar pollen is the most common causative allergen for seasonal allergic rhinitis (AR) in Japan. More commonly known as Japanese cedar pollinosis, it occurs in spring causing the typical symptoms of seasonal AR, such as sneezing, rhinorrhea, nasal obstruction, nasal itching, and itching of the eyes. Previous reports indicate that the prevalence of Japanese cedar pollinosis among Japane...
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ژورنال
عنوان ژورنال: Allergology International
سال: 2016
ISSN: 1323-8930
DOI: 10.1016/j.alit.2015.12.007